Analysts: GSK shingles vaccine could steal market share from Merck's Zostavax
The deciding factor? An advantage for HZ/su in older people.
The incidence of shingles increases with age, but Zostavax's ability to decrease risk of shingles declines in older people, the analysts wrote in a note. If Glaxo's double-blind trial--involving 16,000 people in 18 countries--shows a more "robust" response in the elderly, it would be a key differentiator to Zostavax.
Zostavax is the only shingles vaccine approved in the U.S. and the EU. Merck ($MRK) sold $765 million worth of Zostavax in 2014, but Glaxo's candidate has a chance to undermine its market position.
After approval, the analysts wrote, HZ/su "should be well positioned to capture market share from Zostavax." The analysts' sales forecast for HZ/su in 2017 is £10 million ($14.8 million) and £75 million ($111 million) in 2020.
The revenues would solidify GSK's No. 1 position in the worldwide vaccines market, a position it nabbed after it acquired the bulk of Novartis' ($NVS) vaccines unit. The British drugmaker leapfrogged Merck, which ranked No. 1 in 2013 sales.