FierceBiotech FierceBiotech IT FiercePharma FierceMedicalDevices
FierceBiotech Research FierceVaccines FiercePharma Manufacturing FierceDrugDelivery

Free Newsletter

About | View Sample | Privacy
Related Topics >> alcohol vaccine

Vaccine could give alcoholics 'hangovers' after one drink

Free Newsletter

FierceVaccines is a weekly update on the vaccine industry, with a special focus on the innovations revolutionizing the development and production of vaccines. Join thousands of lab research professionals who get FierceVaccines via weekly email. Sign up today!



Tools

Chilean researchers are developing a vaccine that causes alcoholics to feel the effects of a hangover after just one drink. The shot targets aldehyde dehydrogenase, the enzymes that metabolize alcohol and control alcohol tolerance. About 20 percent of Asians lack aldehyde dehydrogenase, which causes feelings of unease, sweating, nausea and accelerated heartbeat when alcohol is consumed. The shot is designed to cause the same side effects in people who do have the enzymes. "With the vaccine, the desire to consume alcohol will be greatly reduced thanks to these reactions," noted head researcher Juan Asenjo.

The vaccine was tested in mice who were dependant on alcohol. They were able to reduce their alcohol intake by half after receiving the shot. Asenjo hopes see human subjects cut their alcohol intake by up to 95 percent. The group has completed animal trials and plans to begin human testing as early as 2012.

- take a look at the AFP story

Related Articles:
'Happyhour' gene offers new clues to treating alcoholism
Lundbeck preps Phase III trials for alcoholism


SHARE
WITH:
Email Twitter Facebook LinkedIn StumbleUpon
Get Your FREE FierceVaccines Email Newsletter:
Be the first to comment
More stories about alcohol vaccine  

Comments

Post new comment

The content of this field is kept private and will not be shown publicly.

More information about formatting options

CAPTCHA
This question is for testing whether you are a human visitor and to prevent automated spam submissions.