Celldex touted what it called the "consistent, impressive story" of its cancer vaccine Rintega this week as it released positive long-term survival data.
When Novartis picked up a plant from Dendreon three years ago, the Swiss drugmaker said it intended to use it for production of its novel cancer therapies which will be customized to each patient's own immune system T cells. While promising as another cancer fighter, what Novartis and others in the so-called CAR-T field must figure out is how to cost-effectively manufacture such personalized treatments, one of the obstacles that led Dendreon to bankruptcy court.
On August 3, 2011, Dendreon shocked the biotech world by posting weak sales and forecasts for its cancer vaccine Provenge. The numbers blindsided investors, triggering a 64% collapse in Dendreon's share price and spreading panic through the biotech market. But, if U.S. law enforcement has it right, the news came as no surprise to one trader: Vitaly Korchevsky.
In January, Germany's cost watchdog decided that Dendreon's--now Valeant's--Provenge had no added benefit for men with metastatic prostate cancer. But now, it's changing its tune.
It's no secret that when serial acquirer and cost-cutting enthusiast Valeant takes over a company, layoffs are on the way. And for Dendreon, the bankrupt Seattle biotech whose assets the Canadian snatched up last month, they've already begun.
Valeant only just picked up Provenge and other assets from bankrupt Dendreon, but it's already trumpeting positive preliminary data for the flailing cancer vaccine. On Wednesday, it announced Phase II results showing that the immune response from Provenge continues two years after biochemically recurrent prostate cancer patients complete treatment.
It's official: Valeant will be the new owner of Dendreon's Provenge.
Bankrupt Dendreon has finally found a taker for its flailing cancer vaccine, Provenge. It seems serial acquirer Valeant is ready to foray into oncology--and thinks it can turn the therapy around.
Ever since Dendreon's lackluster Provenge launch, the Washington-based biotech's failures have cast a pall over the troubled cancer vaccine field. And the company's bankruptcy won't help with that.
A couple of years ago, Dendreon sold off a manufacturing plant to Novartis for $40 million-plus to raise some quick cash. Now, someone can pick up its two remaining manufacturing facilities, a logistics center and headquarters in Seattle and its one-time promising drug, Provenge, for as little as $275 million.