Researchers at Harvard University have demonstrated that a nonsurgical injection of programmable biomaterial can assemble in vivo into a 3-D structure to attack cancer cells and help to prevent other infectious diseases such as HIV.
The National Institutes of Health recently awarded $20 million to a collaboration of researchers led by the Oak Crest Institute of Science to develop a novel intravaginal ring designed to prevent the spread of sexually transmitted HIV in women by delivering powerful combinations of antiretroviral drugs.
HIV/AIDS prevention can be difficult in countries with limited resources, especially when it comes to the millions of affected children who are less likely to tolerate antiretroviral drugs. In an effort to overcome this challenge, researchers at Penn State University have developed a delivery system for the antiretroviral Ritonavir that uses a protein in cow's milk for oral administration of the drug.
Investigators at Harvard say that they have successfully used CRISPR Cas gene-editing tools to come up with a new approach in curing HIV, a lethal virus that has claimed millions of lives over recent decades. And they're prepping for animal studies now to see if they can provide some preclinical proof-of-concept data to back up their lab experiment.
Investigators at Yerkes National Primate Research Center at Emory University may have found new evidence that dispels the theory that macrophages, a type of white blood cell, may harbor HIV for long periods of time, acting as a reservoir.
Researchers at the Salk Institute for Biological Studies have uncovered a protein that plays a role in active HIV replication, essentially acting as part of a switch to turn HIV-1, the most common type of HIV, from a dormant state to an active one.
Some Indian companies that had put off production of HIV/AIDS meds while they waited for the government to sign contracts are now having to seriously ramp up because of shortages of some meds, Reuters reports.
New technology has allowed researchers to view HIV proteins in action, zooming in on so-called spikes that help the virus bind to cells it infects. The research puts scientists one step closer to a vaccine that could effectively prevent transmission of HIV and halt the spread of AIDS, an international epidemic.
Swiss firm Mymetics is getting a boost from the Bill and Melinda Gates Foundation to conduct a key animal study for its HIV vaccine candidate at the Texas Biomedical Research Institute.
Gilead has been seeking FDA approval for HIV drugs Tybost and Vitekta for a while now, but the agency dealt the drugmaker a setback with Complete Response Letter last year. Now, 17 months later, the two have passed muster.