Topic:

Clinical Trials

Latest Headlines

Latest Headlines

Health system UPMC leads $17M financing for mental health wellness services app

Lantern aims to put mental health services and professionals at the patient's fingertips with its online and mobile programs in cognitive behavioral therapy. To help it do so, Pittsburgh-based healthcare provider and payer UPMC is leading a $17 million investment and it also will partner with the San Francisco-based startup to conduct pilot testing of its approach.

After 2nd positive PhIII, AbbVie points endometriosis drug elagolix to a 2017 NDA

AbbVie says it has racked up a second set of positive Phase III data for its endometriosis drug elagolix, setting up a regulatory filing for sometime next year.

JAK inhibition for solid tumors flops, forcing Incyte to pull the plug on a slate of trials

Jakafi has failed to help patients in a late-stage study for pancreatic cancer, and Incyte feels that it now has all the data it needs to prove that a JAK1 inhibitor is the wrong way to go in solid tumors.

Ferring pits prostate cancer drug against AbbVie's Lupron in PhIIIb CV outcomes study

Ferring Pharmaceuticals is set to put its prostate cancer drug Firmagon up against AbbVie's Lupron in a Phase IIIb trial. The study is designed to assess the cardiovascular safety profile of the gonadotropin-releasing hormone receptor agonist and antagonist, potentially giving Ferring an edge over a product that generated $826 million (€744 million) for AbbVie last year.

Heptares plans PhII Alzheimer's, schizophrenia trials after M1 agonist clears first clinical test

Heptares is gearing up to advance a candidate from its muscarinic M1 receptor agonist program into Phase II in patients with Alzheimer's disease, schizophrenia or Lewy body dementia. While specifics of which drug to aim at which indication are still being decided, Heptares has seen enough in its first clinical data to continue pursuing a target that has shown more promise than most in Alzheimer's.

UPDATED: A patient in Akashi's suspended Duchenne MD trial dies

A little more than a week after Cambridge, MA-based Akashi Therapeutics suspended its study of a new drug for Duchenne muscular dystrophy after a patient was sent to the hospital, the biotech reports that the trial subject has died.

Cellnovo partners with TypeZero in major NIH-backed artificial pancreas trial in Type 1 diabetics

Paris-based Cellnovo Group has partnered with TypeZero Technologies to be part of a previously announced clinical trial of an artificial pancreas that's being backed by a $12.8 million grant from the U.S. National Institutes of Health. Cellnovo's connected insulin patch pump will be used in conjunction with TypeZero's inControl AP software and a Dexcom continuous glucose monitor to form the whole of the artificial pancreas system being tested.

French investigators to Biotrial: You should have stopped fatal study earlier

French Health Minister Marisol Touraine has criticized the CRO behind a botched drug trial that has seen one die and 5 others seriously ill for failing to stop the study.

French authorities still don't know what happened in fatal drug trial

French health regulators have yet to determine exactly went wrong in a drug trial that left one volunteer dead last month, working to establish the cause of a Phase I disaster that has shaken up the drug industry.

Catalent invests more in Asia, beefing up a Singapore supply outpost

Catalent Pharma Solutions is building up its clinical supply capabilities in Asia, expanding a Singapore facility as it works on a sizable expansion in Japan.