Sanofi Pasteur is entering an important period for its vaccine business. The success of its big bet on a dengue fever vaccine hangs on upcoming late phase data. And its clostridium difficile jab has just entered Phase III, too.
Top 10 pharma companies by employees
Being the largest company by any number of measures--revenues, earnings, those kinds of yardsticks--is a good thing. Being the largest by number of employees is trickier, unless yours is also the largest by those other measures. As we have seen time and again in recent years in the pharma industry, having lots of employees and falling revenues is a formula that leads to layoffs. As a whole, the top 10 companies had fewer employees at the end of 2012 than at the end of 2011. Read the full report >>
With the books closed on 2012, we can confirm--as expected--that a majority of the major FDA vaccine approvals went to trivalent influenza vaccines. (The FDA is continuing this trend with the first vaccine approval of 2013 going to Flublok.) Manufacturers, after all, need to reformulate them each season. But two new quadrivalent flu vaccines from GlaxoSmithKline and AstraZeneca also joined the ranks, scheduled to hit the market later this year. Read more >>
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GSK will begin adding 2-D barcodes to its Fluarix Quadrivalent 4-in-1 influenza vaccine, which the FDA cleared for shipping on Monday. Over the next 6 months GSK will add the barcode technology to the packaging of more vaccines.
Researchers have linked rising allergy rates to improved hygiene and asked whether the Bacillus Calmette-Guérin vaccine can reverse the trend. Existing data is inconclusive, but an Australian team has seen enough to run a 1,400-person trial into the effect of the vaccine.
Research in the journal Obstetrics and Gynecology found that 74,000 pregnant women who received a flu shot, in any trimester, were no more likely to experience pregnancy complications.
Sanaria has spent the past decade harvesting parasites from the salivary glands of mosquitoes to use in malaria vaccines. The resulting vaccine uses a weakened form of the whole parasite to generate an immune response.
PharmAthene said the combined company will have four clinical-stage products, giving it the diversified portfolio desired by management.
The approval of MedImmune's nasally-administered FluMist in 2003 was the first major advance in the delivery of influenza vaccines since immunization against the flu began in 1945. This week Vaxart raised $20 million to bring about the next step forward--vaccines in tablet form.
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Merck is cutting back its manufacturing footprint and thus its workforce worldwide. In Ireland, which has suffered from some of that contraction, the company's fortunes are followed closely. But a new report to the government there shows that it actually grew employment at a plant in Swords in spite of falling profits.
Sage Therapeutics has recruited pharmaceutical veteran Dr. Jeffrey Jonas as CEO in a hiring drive that adds decades of industry experience at the two-year-old startup.